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Th occunc hypsnsitivity actions tZYLOPIM (allopuinol) may b incasd in patints with dcasd nal unction civing thiazids and ZYLOPIM (allopuinol) concuntly. this ason, in this clinical stting, such combinations should b administd with caution and patints should b obsvd closly.
Dnot stAllopuinol Sandoz any oth mdicin in th bathoom na a sink. Dnot lav it on a window sill in th ca.
Mylosuppssion potd; us caution whn administing oth dugs known tcaus mylosuppssion.
ZYLOPIM (allopuinol) acts on puin catabo-lism, without disupting th biosynthsis puins. It ducs th poduction uic acid by inhibiting th biochmical actions mmdiatly pcding its omation. ZYLOPIM (allopuinol) is a stuctual analogu th natual puin bas, hypoxanthin. It is an inhibitxanthin oxidas, th nzym sponsibl th convsion hypoxanthin txanthin and xanthin tuic acid, th nd poduct puin mtabolism in man. ZYLOPIM (allopuinol) is mtabolizd tth cosponding xanthin analogu, oxipuinol (alloxanthin), which alsis an inhibitxanthin oxidas.
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