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In these patients, zestril should be started under very close medical supervision and such patients should be followed closely for the first two weeks of treatment and whenever the dose of zestril and or diuretic is increased.
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Do not stop taking your tabletseven if you are feeling wellunless your doctor tells you to.
Severe allergic reactionsrareaffects 1 to 10 users in 10,000The signs may include sudden onset ofSwelling of your facelipstongue or throatThis may make it difficult to swallowSevere or sudden swelling of your handsfeet and anklesDifficulty breathingSevere itching of the skinwith raised lumpsSevere skin disorderslike a suddenunexpected rash or burningred or peeling skinvery rareaffects less than 1 user in 10,000An infection with symptoms such as fever and serious deterioration of your general conditionor fever with local infection symptoms such as sore throat/pharynx/mouth or urinary problemsvery rareaffects less than 1 user in 10,000
Following oral administration of lisinoprilpeak serum concentrations occur within about 7 hoursalthough there was a trend to a small delay in time taken to reach peak serum concentrations in acute myocardial infarction patientsBased on urinary recoverythe mean extent of absorption of lisinopril is approximately 25with interpatient variability of 6-60over the dose range studied5-80 mgThe absolute bioavailability is reduced approximately 16in patients with heart failureLisinopril absorption is not affected by the presence of food.
Initial dose5 mg orallywithin 24 hours of the onset of acute myocardial infarctionSubsequent doses5 mg orally after 24 hoursthen 10 mg orally after 48 hoursMaintenance dose10 mg orally once a dayDosing should continue for at least 6 weeks.
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