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Although not specifically identified in studies with tinidazolethe following drug interactions were reported for metronidazolea chemically-related nitroimidazoleThereforethese drug interactions may occur with tinidazole.
Other than for use in the treatment of giardiasis and amebiasis in pediatric patients older than three years of agesafety and effectiveness of tinidazole in pediatric patients have not been established.
Cholestyramine was shown to decrease the oral bioavailability of metronidazole by 21Thusit is advisable to separate dosing of cholestyramine and tinidazole to minimize any potential effect on the oral bioavailability of tinidazole.
Carcinogenicity has been seen in mice and rats treated chronically with metronidazoleanother nitroimidazole agentAlthough such data have not been reported for tinidazolethe two drugs are structurally related and have similar biologic effectsIts use should be reserved for the conditions described in INDICATIONS AND USAGE.
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pediatric administration for those unable to swallow tablets, tinidazole tablets may be crushed in artificial cherry syrup, to be taken with food.