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Other medications can affect the removal of doxazosin from your bodywhich may affect how doxazosin worksExamples include azole antifungalssuch as itraconazoleketoconazoleboceprevirmacrolide antibioticssuch as clarithromycinHIV protease inhibitorssuch as lopinavirritonaviramong others.

Priapismpainful penile erectionsustained for hours and unrelieved by sexual intercourse or masturbationrarely reportedprobably less frequently than once in every several thousand patientswith alpha-1 antagonistsincluding doxazosinbecause condition can lead to permanent impotence if not promptly treatedpatients must be advised about seriousness of condition.

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Use with caution in liver disease or recent strokecerebrovascular accidentCVARule outprostate cancer before initiating therapy May cause first-dose fainting or sudden loss of consciousness Risk of dizziness upon standingdose dependentPotential for low blood pressuredry mouthand urinary complications in elderly Priapismpainful penile erectionsustained for hours and unrelieved by sexual intercourse or masturbationrarely reportedprobably less frequently than once in every several thousand patientswith alpha-1 antagonistsincluding doxazosinbecause condition can lead to permanent impotence if not promptly treatedpatients must be advised about seriousness of condition Concomitant use of other antihypertensivesadditive hypotensive effectsExtended-release form not indicated for high blood pressure Concomitant administration of immediate-release form with a phosphodiesterase-5PDE-5inhibitor can result in additive blood pressure lowering effects and symptomatichypotension May increase the risk of heart failure by exacerbating underlying myocardial dysfunction by beta-1Receptor stimulation with increases in renin and aldosterone.

Other medications can affect the removal of doxazosin from your bodywhich may affect how doxazosin worksExamples include azole antifungalssuch as itraconazoleketoconazoleboceprevirmacrolide antibioticssuch as clarithromycinHIV protease inhibitorssuch as lopinavirritonaviramong others.

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