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Cerebral hemorrhagesubarachnoid hemorrhageand stroke have occurred in patients treated with 5-HT 1 agonistsand some have resulted in fatalitiesIn a number of casesit appears possible that the cerebrovascular events were primarythe 5-HT 1 agonist having been administered in the incorrect belief that the symptoms experienced were a consequence of migraine when they were notAlsopatients with migraine may be at increased risk of certain cerebrovascular eventse.gstrokehemorrhageTIADiscontinue Imitrex tablets if a cerebrovascular event occurs.

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3Treatment of migraine attacks with sumatriptanthe subcutaneous sumatriptan international study groupN Engl J Med 3251991316-21.

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imitrex tablets contain sumatriptan succinate, a selective 5 ht 1b 1d receptor agonist.

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