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Call your doctor if you have unusual bruising or bleedingor signs of infectionfeverchillsbody aches

Examples of drugs that can cause interactions with methotrexate are listed below.

The good newsThese side effects can often be short-circuited by taking a folic acid supplementFolic acid is the synthetic form of folateOne study found that RA patients on methotrexate who took folic acid supplements lowered the risk of GI problems and mouth sores by 79 percent.

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