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Nausea and vomiting commonly occur with cyclophosphamide therapyAnorexia andless frequentlyabdominal discomfort or pain and diarrhea may occurThere are isolated reports of hemorrhagic colitisoral mucosal ulceration and jaundice occurring during therapyThese adverse drug effects generally remit when cyclophosphamide treatment is stopped.

The Cytoxan brand name has been discontinued in the U.SIf generic versions of this product have been approved by the FDAthere may be generic equivalents available.

DUse in LIFE-THREATENING emergencies when no safer drug availablePositive evidence of human fetal risk.

When Cytoxan is included in combined cytotoxic regimensit may be necessary to reduce the dose of Cytoxan as well as that of the other drugs.

Information on adverse reactions associated with the use of Cytoxancyclophosphamideis arranged according to body system affected or type of reactionThe adverse reactions are listed in order of decreasing incidenceThe most serious adverse reactions are described in the WARNINGS section.

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