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Amitriptyline inhibits the membrane pump mechanism responsible for uptake of norepinephrine and serotonin in adrenergic and serotonergic neuronsPharmacologically this action may potentiate or prolong neuronal activity since reuptake of these biogenic amines is important physiologically in terminating transmitting activityThis interference with the reuptake of norepinephrine and/or serotonin is believed by some to underlie the antidepressant activity of amitriptyline.

Take this medication regularly in order to get the most benefit from itTo help you remembertake it at the same time(seach dayDo not increase your dose or use this drug more often or for longer than prescribedYour condition will not improve any fasterand your risk of side effects will increase.

Antidepressant medications are used to treat a variety of conditionsincluding depression and other mental/mood disordersThese medications can help prevent suicidal thoughts/attempts and provide other important benefitsHoweverstudies have shown that a small number of peopleespecially people younger than 25who take antidepressants for any condition may experience worsening depressionother mental/mood symptomsor pharmacy one line. suicidal thoughts/attemptsThereforeit is very important to talk with the doctor about the risks and benefits of antidepressant medicationespecially for people younger than 25even if treatment is not for a mental/mood conditionTell the doctor right away if you notice worsening depression/other psychiatric conditionsunusual behavior changesincluding possible suicidal thoughts/attemptsor other mental/mood changesincluding new/worsening anxietypanic attackstrouble sleepingirritabilityhostile/angry feelingsimpulsive actionssevere restlessnessvery rapid speechBe especially watchful for these symptoms when a new antidepressant is started or when the dose is changed.

For PainWas prescribed Elavil mainly for chronic headachesAlso suffer from depressionanxiety and insomnia so my neurologist had me start Elavil to try and kill many birds with one stoneso to speakElavil worked great to reduce the intensity of my headachesAlthough they were still going on it was much more tolerableI had been on Elavil only one month and a week before I stoppedFirst week my insomnia and anxiety seemed to be simmering downThis stopped soon after week 2As for my depressionElavil put it under a magnifying glassI was suicidal and crying on a daily basisit was not the medication for meIt helped with the main objective but at a horrible cost

Amitriptyline inhibits the membrane pump mechanism responsible for uptake of norepinephrine and serotonin in adrenergic and serotonergic neuronsPharmacologically this action may potentiate or prolong neuronal activity since reuptake of these biogenic amines is important physiologically in terminating transmitting activityThis interference with the reuptake of norepinephrine and/or serotonin is believed by some to underlie the antidepressant activity of amitriptyline.

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