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In the treatment of infections due to Streptococcus pyogenesa therapeutic dosage of cefixime should be administered for at least 10 days.

SUPRAX may be administered in the presence of impaired renal functionNormal dose and schedule may be employed in patients with creatinine clearances of 60 mL/min or greaterRefer to Table 2 for dose adjustments for adults with renal impairmentNeither hemodialysis nor peritoneal dialysis removes significant amounts of drug from the body.

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Severe cutaneous reactionsincluding Stevens-Johnson syndromeepidermal necrolysisand drug rash with eosinophilia and systemic symptomsDRESSreporteddiscontinue therapy and implement supportive therapy if reaction occurs.

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