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Ft-ir spectrum of treated tetracycline showed the downstream shifting of aromatic c-h stretching from 3085-3024 cm-1 to 3064-3003 cm-1 and c c stretching from 1648-1582 cm-1 to 1622-1569 cm-1 and up shifting of c-n stretching from 965 cm-1 to 995 cm-1.
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Tetracyclines penetrate into most body tissues and fluidsAll are concentrated in unobstructed bileHoweverCSF levels are not reliably therapeuticMinocycline is the only tetracycline that reaches high concentrations in tears and saliva.
Do not use this medication if you are allergic to tetracyclineor to similar medicines such as demeclocyclineDeclomycindoxycyclineAdoxaDoryxOraceaVibramycinor minocyclineDynacinMinocinSolodynVectrin
Antibiotic medicines can cause diarrheawhich may be a sign of a new infectionIf you have diarrhea that is watery or has blood in itcall your doctorDo not use any medicine to stop the diarrhea unless your doctor has told you to.
Do not use this medication if you are pregnantIt could cause harm to the unborn babyincluding permanent discoloration of the teeth later in lifeTetracycline can make birth control pills less effectiveUse a second method of birth control while you are taking tetracycline to keep from getting pregnant.
Do not take iron supplementsmultivitaminscalcium supplementsantacidsor laxatives within 2 hours before or after taking tetracyclineThese products can make tetracycline less effective.
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although pseudomembranous colitis had initially been noted most commonly with the administration of clindamycin, virtually all antibiotics especially ampicillin, cephalosporins, and tetracyclines have since been associated with this infection.